Extending Unbiased Stereology of Brain Ultrastructure to Three-dimensional Volumes
نویسندگان
چکیده
منابع مشابه
Extending Unbiased Stereology of Brain Ultrastructure to Three-dimensional Volumes
Design and Measurements: Volumes are reconstructed by defining transformations that align the entire area of adjacent sections. Whole-field alignment requires rotation, translation, skew, scaling, and second-order nonlinear deformations. Such transformations are implemented by a linear combination of bivariate polynomials. Computer software for generating transformations based on user input is ...
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OBJECTIVE Analysis of brain ultrastructure is needed to reveal how neurons communicate with one another via synapses and how disease processes alter this communication. In the past, such analyses have usually been based on single or paired sections obtained by electron microscopy. Reconstruction from multiple serial sections provides a much needed, richer representation of the three-dimensional...
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ژورنال
عنوان ژورنال: Journal of the American Medical Informatics Association
سال: 2001
ISSN: 1067-5027,1527-974X
DOI: 10.1136/jamia.2001.0080001